http://www.cancer-blog.org/blogs/cancer-blog.html Cancer blog From Cancer blog Thu, 07 Jul 2011 14:58:59 GMT en-us http://www.cancer-blog.org/images/blogs/cancer-blog-3490.jpg http://www.cancer-blog.org/blogs/cancer-blog.html 104 97 http://www.cancer-blog.org/blogs/permalinks/7-2011/disparities-in-progress-against-colorectal-cancer.html http://www.cancer-blog.org/blogs/permalinks/7-2011/disparities-in-progress-against-colorectal-cancer.html Thu, 07 Jul 2011 14:58:59 GMT Progress in reducing colorectal cancer (CRC) mortality rates varies significantly across states, with rates in the Northeast showing the most progress and those in the South showing the least progress, as per a newly released study. As a result, the highest burden of CRC mortality shifted from the Northeast in the early part of 1990s to the southern states along the Appalachian corridor in the mid 2000s. The decrease in CRC mortality rates by state correlated strongly with uptake of screening........ ]]> http://www.cancer-blog.org/blogs/permalinks/4-2011/kras-rearrangements-in-metastatic-prostate-cancer.html http://www.cancer-blog.org/blogs/permalinks/4-2011/kras-rearrangements-in-metastatic-prostate-cancer.html Thu, 07 Jul 2011 14:58:59 GMT Researchers have uncovered a genetic characteristic of metastatic prostate cancer that defines a rare sub-type of this disease. These findings appear in Cancer Discovery, the newest journal of the American Association for Cancer Research, which will debut at the AACR 102nd Annual Meeting 2011, held April 2-6........ ]]> http://www.cancer-blog.org/blogs/permalinks/3-2011/molecular-disease-model-for-melanoma.html http://www.cancer-blog.org/blogs/permalinks/3-2011/molecular-disease-model-for-melanoma.html Thu, 07 Jul 2011 14:58:59 GMT Cancer Commons, an initiative of CollabRx, a provider of information technology to personalize cancer therapys and accelerate research, announces the publication of a molecular disease model of melanoma (MDMM) which classifies the disease into molecular subtypes, rather than traditional histological or cellular subtypes, and describes therapy guidelines for each subtype, including specific assays, drugs, and clinical trials. The paper, titled "Molecular Disease Model for Melanoma," by Vidwans et al, was reported in the March 30th issue of PLoS ONE....... ]]> http://www.cancer-blog.org/blogs/permalinks/3-2011/potential-cancer-therapy.html http://www.cancer-blog.org/blogs/permalinks/3-2011/potential-cancer-therapy.html Thu, 07 Jul 2011 14:58:59 GMT Alpha viruses, such as Sindbis virus, carry their genetic information on a single strand of RNA. On infection they use a protein, replicase, to produce double stranded RNA (dsRNA) which is used as genetic material to make more viruses. However the body recognizes dsRNA as foreign, and infected cells initiate an immune response. New research published in BioMed Central's open access journal BMC Cancer demonstrates that an artificial plasmid coding for the replicase genes of Sindbis virus causes regression and destruction of lung cancer, or melanoma, cells in mice........ ]]> http://www.cancer-blog.org/blogs/permalinks/3-2011/prostate-cancer-radiation-treatment.html http://www.cancer-blog.org/blogs/permalinks/3-2011/prostate-cancer-radiation-treatment.html Thu, 07 Jul 2011 14:58:59 GMT Prostate cancer is something that makes anyone nervous. Instead of going into this battle alone, there are many resources you can use to help you understand what you are up against. If prostate cancer radiation treatment is something that you will be undergoing, you might have many questions. ....... ]]> http://www.cancer-blog.org/blogs/permalinks/2-2011/cancer-cells-as-ancient-toolkit.html http://www.cancer-blog.org/blogs/permalinks/2-2011/cancer-cells-as-ancient-toolkit.html Thu, 07 Jul 2011 14:58:59 GMT Despite decades of research and billions of dollars, cancer remains a major killer, with an uncanny ability to evade both the body's defenses and medical intervention. Now an Arizona State University scientist believes he has an explanation. "Cancer is not a random bunch of selfish rogue cells behaving badly, but a highly-efficient pre-programmed response to stress, honed by a long period of evolution," claims professor Paul Davies, director of the BEYOND Center for Fundamental Concepts in Science at ASU and principal investigator of a major research program funded by the National Cancer Institute designed to bring insights from physical science to the problem of cancer........ ]]> http://www.cancer-blog.org/blogs/permalinks/2-2011/a-loose-grip-provides-better-chemotherapy.html http://www.cancer-blog.org/blogs/permalinks/2-2011/a-loose-grip-provides-better-chemotherapy.html Thu, 07 Jul 2011 14:58:59 GMT cientists at Case Western Reserve University have developed a little bomb that promises a big bang for cancer patients. Preliminary tests show an anti-cancer drug loosely attached to gold nanoparticles starts accumulating deep inside tumors within minutes of injection and can be activated for an effective therapy within two hours. The same drug injected alone takes two days to gather and attacks the tumor from the surface � a far less effective route........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/y-90-radioembolization-for-liver-cancer.html http://www.cancer-blog.org/blogs/permalinks/12-2010/y-90-radioembolization-for-liver-cancer.html Thu, 07 Jul 2011 14:58:59 GMT he latest weapon against inoperable liver cancer is so tiny that it takes millions of them per therapy, but as per interventional radiologists at the Indiana University School of Medicine, those microscopic spheres really pack a therapeutic punch. The glass spheres contain a radioactive element, yttrium-90, more usually known as Y-90, which emits radiation for a very limited distance so that healthy tissue around the tumor remains unaffected. (2.5mm or less than 1/16th inch in soft tissue)........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/prognosis-with-circulating-tumor-cells.html http://www.cancer-blog.org/blogs/permalinks/12-2010/prognosis-with-circulating-tumor-cells.html Thu, 07 Jul 2011 14:58:59 GMT etastatic breast cancer patients whose blood contains circulating tumor cells (CTCs) before or after treatment with high-dose chemotherapy and blood stem cell transplant have shorter survival periods, according to a new study by researchers at The University of Texas MD Anderson Cancer Center in Houston........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/triple-negative-breast-cancer.html http://www.cancer-blog.org/blogs/permalinks/12-2010/triple-negative-breast-cancer.html Thu, 07 Jul 2011 14:58:59 GMT gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center researchers during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/pomegranate-juice-components-inhibit-cancer.html http://www.cancer-blog.org/blogs/permalinks/12-2010/pomegranate-juice-components-inhibit-cancer.html Thu, 07 Jul 2011 14:58:59 GMT Scientists at the University of California, Riverside (UCR), have identified components in pomegranate juice that seem to inhibit the movement of cancer cells and weaken their attraction to a chemical signal that has been shown to promote the metastasis of prostate cancer to the bone, as per a presentation today at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/types-of-reconstruction.html http://www.cancer-blog.org/blogs/permalinks/12-2010/types-of-reconstruction.html Thu, 07 Jul 2011 14:58:59 GMT acing mastectomy (the removal of one or both breasts frequently due to cancer-as opposed to lumpectomy, which just removes a small portion of the breast) can be an emotional, challenging time for women who have been diagnosed with breast cancer. The act of thinking beyond the present and looking forward to moving on with one's life in the future has given a number of women the strength to make it through each day. If your doctor has advised mastectomy, now is also an appropriate time to start asking about the next step: breast reconstruction........ ]]> http://www.cancer-blog.org/blogs/permalinks/12-2010/a-small-molecule-against-cancer.html http://www.cancer-blog.org/blogs/permalinks/12-2010/a-small-molecule-against-cancer.html Thu, 07 Jul 2011 14:58:59 GMT A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53. Michael Andreeff, M.D., Ph.D., professor of Medicine and chief of Molecular Hematology and Therapy in the Department of Leukemia at The University of Texas MD Anderson Cancer Center, presented preliminary results of this ongoing Phase I study at the 52nd Annual Meeting of the American Society of Hematology. The clinical trial is under way at MD Anderson and five other sites in the United States and United Kingdom........ ]]> http://www.cancer-blog.org/blogs/permalinks/10-2010/gene-prevents-stem-cells-from-turning-cancerous.html http://www.cancer-blog.org/blogs/permalinks/10-2010/gene-prevents-stem-cells-from-turning-cancerous.html Thu, 07 Jul 2011 14:58:59 GMT Stem cells, the prodigious precursors of all the tissues in our body, can make almost anything, given the right circumstances. Including, unfortunately, cancer. Now research from Rockefeller University shows that having too a number of stem cells, or stem cells that live for too long, can increase the odds of developing cancer. By identifying a mechanism that regulates programmed cell death in precursor cells for blood, or hematopoietic stem cells, the work is the first to connect the death of such cells to a later susceptibility to tumors in mice. It also provides evidence of the potentially carcinogenic downside to stem cell therapys, and suggests that nature has sought to balance stem cells' regenerative power against their potentially lethal potency........ ]]> http://www.cancer-blog.org/blogs/permalinks/9-2010/nose-drops-to-treat-brain-cancer.html http://www.cancer-blog.org/blogs/permalinks/9-2010/nose-drops-to-treat-brain-cancer.html Thu, 07 Jul 2011 14:58:59 GMT Scientists are reporting the development and successful initial testing of a new form of methotrexate the mainstay anticancer drug designed to be given as nose drops rather than injected. It shows promise as a more effective treatment for brain cancer, they say. The report appears in ACS' Molecular Pharmaceutics, a bi-monthly journal........ ]]> http://www.cancer-blog.org/blogs/permalinks/9-2010/new-frontier-in-fighting-cancer.html http://www.cancer-blog.org/blogs/permalinks/9-2010/new-frontier-in-fighting-cancer.html Thu, 07 Jul 2011 14:58:59 GMT A "game-changing" technique using near infrared light enables researchers to look deeper into the guts of cells, potentially opening up a new frontier in the fights against cancer and a number of other diseases. University of Central Florida chemists, led by Professor Kevin Belfield, used near infrared light and fluorescent dye to take pictures of cells and tumors deep within tissue. The probes specifically target lysosomes, which act as cells' thermostats and waste processors and which have been associated with a variety of diseases, including types of mental illnesses and cancers........ ]]> http://www.cancer-blog.org/blogs/permalinks/8-2010/inhibiting-prostate-cancer.html http://www.cancer-blog.org/blogs/permalinks/8-2010/inhibiting-prostate-cancer.html Thu, 07 Jul 2011 14:58:59 GMT A kinase is a type of enzyme the body uses to regulate the functions of the proteins mandatory for cell growth and maintenance, and scientists have discovered that one in particular plays a key role in developing prostate cancer. "It's known as Mnk, and eventhough it appears not to be essential for normal cell maintenance, it's important for cancer growth" said Dr. Luc Furic, a postdoctoral researcher working with Dr. Nahum Sonenberg at McGill University's Goodman Cancer Research Centre and Department of Biochemistry........ ]]>