New frontier in fighting cancerA "game-changing" technique using near infrared light enables researchers to look deeper into the guts of cells, potentially opening up a new frontier in the fights against cancer and a number of other diseases.
University of Central Florida chemists, led by Professor Kevin Belfield, used near infrared light and fluorescent dye to take pictures of cells and tumors deep within tissue. The probes specifically target lysosomes, which act as........Go to the Cancer-blog (Added on 9/1/2010 6:59:04 AM)
Reducing pain and depression of cancerPain and depression linked to cancer symptoms often unrecognized and undertreated can be significantly reduced through centralized telephone-based care management coupled with automated symptom monitoring, as per scientists from the Regenstrief Institute and Indiana University School of Medicine.
The Indiana Cancer Pain and Depression (INCPAD) study combined automated calls with follow-up calls from the nurse care manager to reduce pain........Go to the Cancer-blog (Added on 7/14/2010 7:50:45 AM)
DNA discovery opens new doorBy solving the three-dimensional structure of a protein involved in repairing DNA errors, a group of McMaster University scientists have revealed new avenues to develop evaluation tools and alternative therapys for people living with hereditary colorectal cancers.
The finding, reported in the journal Molecular Cell, is an important step forward in the field of molecular and structural biology. The McMaster scientists uncovered how a specific........Go to the Cancer-blog (Added on 7/9/2010 7:28:02 AM)
Off-the-shelf digital camera for cancer detectionUsing an off-the-shelf digital camera, Rice University biomedical engineers and scientists from the University of Texas M.D. Anderson Cancer Center have created an inexpensive device that is powerful enough to let doctors easily distinguish malignant cells from healthy cells simply by viewing the LCD monitor on the back of the camera.
The results of the first tests of the camera were published online this week in the open-access journal PLoS........Go to the Cancer-blog (Added on 6/24/2010 10:20:19 PM)
Racial disparities diminish in specialized cancer centersA newly released study has observed that when African American and white cancer patients are treated at similar, specialized cancer care institutions, mortality rates are roughly equal. Published early online in Cancer, a peer-evaluated journal of the American Cancer Society, the findings suggest that where patients receive care may partly explain observed racial disparities in cancer mortality.
In the newly released study, scientists led by........Go to the Cancer-blog (Added on 3/22/2010 7:39:44 PM)
Community Hospitals as Safe Surgical OptionLow-risk patients who require certain cancer surgeries can have the procedures performed with low operative mortality rates at community hospitals, as per a newly released study.
The research showed that for 13 different kinds of cancer surgeries such as gastric and colon, younger patients with few pre-existing illnesses survived operations at community hospitals at a similar rate as at cancer centers.
But patients who are considered high........Go to the Cancer-blog (Added on 2/3/2010 7:58:13 AM)
Quality radiation therapyThe American Association of Physicists in Medicine (AAPM) has issued a statement today in the wake of several recent articles in the New York Times yesterday and earlier in the week that discuss many rare but tragic events in the last decade involving people undergoing radiation treatment.
While it does not specifically comment on the details of these events, the statement acknowledges their gravity. It reads in part: "The AAPM and its........Go to the Cancer-blog (Added on 2/1/2010 8:09:56 AM)
Targeting stem cells to fight ovarian cancerEliminating cancer stem cells (CSCs) within a tumor could hold the key to successful therapys for ovary cancer, which has been notoriously difficult to detect and treat, as per new findings published this week in the journal Oncogene by Yale School of Medicine researchers.
"We observed that stopping the expression of two genesLin28 and Oct4reduces ovary cancer cell growth and survival," said Yingqun Huang, M.D., assistant professor in the........Go to the Cancer-blog (Added on 1/28/2010 7:54:44 AM)
Robotic surgery for kidney cancerFox Chase Cancer Center scientists find that outcomes of robotic assisted kidney cancer surgery, when performed by experienced surgeons at high volume centers, prove more beneficial to patients when in comparison to open surgery. The study, authored by Fox Chase robotic surgeon Rosalia Viterbo, MD, was presented today at the American Urological Association's Annual Meeting, .
The standard therapy for kidney cancer is to surgically remove........Go to the Cancer-blog (Added on 4/27/2009 5:17:51 AM)
How radiation therapy causes chronic inflammation of bowelsThe use of radiation treatment to treat cancer inevitably involves exposure of normal tissues. Eventhough the benefits of this therapy have been well established, many patients experience distressing complications as a result injury to normal tissue These side effects correlation to inflammatory process cause discomfort and decreases the therapeutic benefit by increasing the overall therapy time.
A research article would be published on........Go to the Cancer-blog (Added on 12/24/2008 5:11:48 AM)
New platinum-phosphate compounds kill ovarian cancerA new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, as per a new study published this week in the journal Proceedings of the National Academy of Sciences.
The compounds could be less harmful than current cancer therapys on the market such as cisplatin and carboplatin because they don't penetrate the cell nucleus and attach........Go to the Cancer-blog (Added on 11/19/2008 8:09:26 PM)
Death, Division or Cancer?Each day, a staggering number of cells perform a feat that still amazes scientists with its complexity: they divide to produce perfect replicas of each other. The process is called mitosis, and an inability to control it is one of the hallmarks of cancer.
Little is known about the biochemical processes that control mitosis, but now scientists from Fox Chase Cancer Center and Technion-Israel Institute of Technology in Haifa, Israel, have........Go to the Cancer-blog (Added on 7/1/2008 10:01:36 PM)
Researchers control growth rate of blood vesselsScientists have discovered a way to control the growth rate of replacement tissue and the formation of new blood vessels, which solves one of the vexing problems of growing replacement tissue to treat injuries and trauma in humans.
The procedure could be used in bone grafts, tissue replacement, dental procedures or for diabetics or elderly patients who experience wound healing problems, said William Giannobile, professor at the University of........Go to the Cancer-blog (Added on 3/9/2008 6:09:04 PM)
|
|
Inhibiting prostate cancerA kinase is a type of enzyme the body uses to regulate the functions of the proteins mandatory for cell growth and maintenance, and scientists have discovered that one in particular plays a key role in developing prostate cancer. "It's known as Mnk, and eventhough it appears not to be essential for normal cell maintenance, it's important for cancer growth" said Dr. Luc Furic, a postdoctoral researcher working with Dr. Nahum Sonenberg at McGill........Go to the Cancer-blog (Added on 8/10/2010 7:14:57 AM)
Multicolor quantum dots in cancer diagnosisThe tunable fluorescent nanoparticles known as quantum dots make ideal tools for distinguishing and identifying rare cancer cells in tissue biopsies, Emory and Georgia Tech researchers have demonstrated.
An article to be featured on the cover of the July 15 issue of Analytical Chemistry describes how multicolor quantum dots associated with antibodies can distinguish the Reed-Sternberg cells that are characteristic of Hodgkin's lymphoma.
........Go to the Cancer-blog (Added on 7/7/2010 7:23:53 AM)
Automated telephone remindersSimple, automated telephone reminders can increase colon cancer screening rates by 30 percent, as per a Kaiser Permanente Center for Health Research study funded by the National Cancer Institute that appears in the July print edition of Medical Care
The study which is the first to examine whether automated calls can increase screening for colon cancer involved nearly 6,000 Kaiser Permanente members in Oregon and Washington who were overdue........Go to the Health-blog (Added on 6/24/2010 11:20:25 PM)
Natural Compound that Inhibits Cancer Cell MigrationInvestigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research) led by Kristiina Vuori, M.D., Ph.D., have discovered that the natural compound sceptrin, which is found in marine sponges, reduces cancer cell motility (movement) and has very low toxicity. Metastasis is one of the deadliest aspects of cancer, so restricting aberrant cell movement is an important step towards advancing........Go to the Cancer-blog (Added on 2/18/2010 9:50:54 PM)
How to kill pediatric brain tumorsScientists at Washington University School of Medicine in St. Louis have shown once again that "ready, fire, aim," nonsensical though it may sound, can be an essential approach to research.
The researchers robotically "fired" 2,000 compounds into culture plates containing tumor cells to see if the compounds had any effect. When the robotic screener found one substance had scored a hit by inhibiting growth of the tumor cells in its plate,........Go to the Cancer-blog (Added on 2/10/2010 8:04:49 AM)
Assessing risks associated with low-dose radiationThere remains a lack of consensus amongst the medical and scientific communities about any cancer risk from low level radiation, especially low-dose radiation delivered from computed tomography (CT) scans. However, the study of epigenetics may play a role in determining whether or not future trends of diseases can in fact be associated with utilization of CT, as per an article in the recent issue of the Journal of the American College of........Go to the Cancer-blog (Added on 2/1/2010 7:39:41 AM)
Reversing Cancer Cell Metabolism And Tumor GrowthA team of researchers led by Professor Adrian Krainer, Ph.D., of Cold Spring Harbor Laboratory has discovered molecular factors in cancer cells that boost the production of an enzyme that helps alter the cells' glucose metabolism. The altered metabolic state, called the Warburg effect, promotes extremely rapid cell proliferation and tumor growth.
Discovered eighty years ago by Nobel Prize-winning scientist Otto Warburg, this altered........Go to the Cancer-blog (Added on 1/25/2010 8:11:42 AM)
Improved detection of bladder tumorsMaking tumors inside the bladder fluoresce red under blue light allows physicians to more easily find and remove them, substantially reducing the rate at which these cancers come back, says a Mayo Clinic doctor who is presenting results of a large, multicenter international clinical trial.
VIDEO ALERT: Additional audio and video resources, including excerpts from an interview with Dr. Lance Mynderse describing the research, are available on........Go to the Cancer-blog (Added on 4/27/2009 5:22:29 AM)
SIRT1 takes down tumorsYuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online April 13 (www.jcb.org) and will appear in the April 20 print issue of the Journal of Cell Biology
The yeast and nematode equivalents of SIRT1 are fountains of youth that stretch lifespan. Whether SIRT1 slows aging in mammals isn't........Go to the Cancer-blog (Added on 4/13/2009 1:32:48 PM)
New therapy prevents dangerous side effect for lymphoma patientsPatients respond well to a new three-drug combination for indolent B cell lymphoma that also spares them prolonged, potentially lethal, suppression of blood production in the bone marrow, scientists at The University of Texas M. D. Anderson Cancer Center report today at the 50th annual meeting of the American Society of Hematology.
Pentostatin, cyclophosphamide and rituximab together are providing the same remission rate as other........Go to the Cancer-blog (Added on 12/9/2008 10:29:32 PM)
Predicting prostate cancer treatment failureDynamic contrast-enhanced MRI (DCE-MRI) plus diffusion weighted imaging (DWI) can accurately diagnose residual or recurrent prostate cancer in patients treated with high-intensity focused ultrasonic ablation, a new study shows.
The study included 27 patients who had increased levels of prostate specific antigen after being treated with high-intensity focused ultrasonic (HIFU) ablation; 18 of these patients had local tumor progression seen at........Go to the Cancer-blog (Added on 5/19/2008 6:40:36 PM)
Drug fends off kidney cancer progressionNew data from an international, multicenter Phase III clinical trial has observed that the experimental targeted treatment everolimus (RAD001) significantly delays cancer progression in patients with metastatic kidney cancer whose disease had worsened on other therapys. The study was led by Robert Motzer, MD, an attending doctor at Memorial Sloan-Kettering Cancer Center (MSKCC), who will present the findings on May 31 at the annual meeting of........Go to the Cancer-blog (Added on 5/18/2008 9:45:02 PM)
|
